Few (if any) other health care interventions have been assessed as extensively as chiropractic spinal manipulation, both in terms of safety and effectiveness. Furthermore, few other health care professions have been as thoroughly researched as chiropractic.

There have been at least six formal government inquiries into chiropractic worldwide over the last 25 years (including Canada, Australia, New Zealand and Sweden). All have concluded that contemporary chiropractic care is safe, effective, cost-effective and have recommended public funding for chiropractic services.

In addition to government inquiries, there have been many scientific clinical studies (randomized controlled trials included) assessing the appropriateness, effectiveness and/or cost-effectiveness of spinal manipulation or chiropractic manipulation (most notably for back pain).